The Osaka–Kansai region stands at the forefront of deeptech, leading in life sciences, biotech, healthcare, greentech, and digital technologies. With strong academic roots and a thriving startup ecosystem, it is emerging as a global hub for transformative solutions.
| Company | Featured | Location | Founding Year | Academic Startup |
|---|---|---|---|---|
 Cross Medicine | DeeptechDX | Tokushima | 2022 | Tokushima University |
 Cubec | Life science | Osaka | 2023 | National Cardiovascular Center |
 DATAGRID | DeeptechDX | Tokyo | 2017 | Kyoto University |
 DIFF. | Life science | Osaka | 2022 | — |
 DeepForest Technologies | DeeptechGreentech | Kyoto | 2022 | Kyoto University |
 Dincula | Life science | Osaka | 2024 | Kansai University |
 E-ThermoGentek | DeeptechGreentech | Kyoto | 2013 | The University of Osaka |
 ER Stress Research Institute | DeeptechLife science | Tokushima | 2017 | Tokushima University |
 ERRAI | Deeptech | Kyoto | 2023 | Kyoto University |
 EVA Therapeutics | Life science | Osaka | 2021 | Tokyo University of Science |
 EX-Fusion | Deeptech | Osaka | 2021 | Osaka University |
 Egret Lab | DeeptechLife science | Tokushima | 2023 | Tokushima University |
 Eight Knot | DX | Osaka | 2021 | — |
 Elcyo | Life science | Kyoto | 2019 | Osaka University |
 EneCoat Technologies | DeeptechGreentech | Kyoto | 2018 | Kyoto University |
 Enishia | DeeptechLife science | Kyoto | 2017 | Kyoto University |
 Eplus | Greentech | Osaka | 2012 | — |
 Evcare | Life science | Shiga | 2019 | Shiga University |
 FLOSFIA | DeeptechGreentech | Kyoto | 2011 | Kyoto University |
 FLUGELZ | Life science | Kyoto | 2025 | Kyoto University |
Driving transformative solutions through cutting-edge research. In Osaka, strong collaboration between academia and industry fosters a thriving Deeptech ecosystem that supports sustainable growth.
Tackling energy transition and environmental challenges head-on, Osaka is leading the way toward a sustainable future through the deployment of renewable energy and decarbonization technologies.
A global hub for medicine, biotechnology, and healthcare. With its concentration of universities and research institutions, Osaka is advancing drug discovery and next-generation medical technologies.
AI, IoT, and data science are fueling Osaka's growth. The city is emerging as a hub of digital transformation, building the foundation for next-generation industries.
2021 to 2024 saw between eight and fourteen Kansai startups achieve IPO annually, pushing the region to the forefront of Japan's startup ecosystem.
Osaka alone is home to over 380 university-originated startups, ranking second only to Tokyo nationwide. When joined with other areas in Kansai, like Kyoto and Hyogo, Kansai proves fertile soil for university spinouts.
Between 2020 and 2023, startups in Osaka, Kyoto, and Hyogo collectively raised over 490 billion yen. Osaka in particular more than doubled funds raised, from ¥111B in 2020 to ¥237B in 2023.
Osaka's university-originated startups offer an excellent spread, from life sciences (24%) and software (23%) to energy (15%) and robotics (12%).