The Osaka–Kansai region stands at the forefront of deeptech, leading in life sciences, biotech, healthcare, greentech, and digital technologies. With strong academic roots and a thriving startup ecosystem, it is emerging as a global hub for transformative solutions.
| Company | Featured | Location | Founding Year | Academic Startup |
|---|---|---|---|---|
 MILAI Technologies | DX | Tokushima | 2020 | Tokushima University |
 MaRI | DeeptechLife science | Kyoto | 2017 | Kyoto University |
 Malignant Tumor Treatment Technologies | DeeptechLife science | Osaka | 2018 | — |
 MeDiCU | DX | Osaka | 2023 | — |
 Megakaryon Corporation | DeeptechLife science | Kyoto | 2011 | Kyoto University, The University of Tokyo |
 Metro Weather | Deeptech | Kyoto | 2015 | Kyoto University |
 MiCAN Technologies | DeeptechLife science | Kyoto | 2016 | Kyoto University, Kumamoto University, The University of Osaka |
 Micro Bio Factory | Life science | Osaka | 2018 | — |
 Microwave Chemical | DeeptechGreentech | Osaka | 2007 | The University of Osaka |
 Millde | Life science | Osaka | 2024 | Osaka University |
 Mitani Battery Co | Greentech | Osaka | 2017 | Osaka Metropolitan University |
 Mormil | DeeptechLife science | Nara | 2022 | Nara Medical University, Tokushima University |
 MotorAI | DX | Shiga | 2023 | Ritsumeikan University |
 NOBIAS | Life science | Osaka | 2018 | Osaka Metropolitan University |
 NT GIKEN Industries | Greentech | Osaka | 2022 | — |
 NUProtein | Life science | Hyogo | 2016 | Nagoya University |
 NanoSpike | Life science | Tokyo | 2025 | Kansai University |
 NeoCure | Life science | Kyoto | 2025 | Osaka University |
 NeuralPort | DeeptechLife science | Hyogo | 2020 | The University of Osaka |
 New Innovations | DX | Tokyo | 2018 | — |
Driving transformative solutions through cutting-edge research. In Osaka, strong collaboration between academia and industry fosters a thriving Deeptech ecosystem that supports sustainable growth.
Tackling energy transition and environmental challenges head-on, Osaka is leading the way toward a sustainable future through the deployment of renewable energy and decarbonization technologies.
A global hub for medicine, biotechnology, and healthcare. With its concentration of universities and research institutions, Osaka is advancing drug discovery and next-generation medical technologies.
AI, IoT, and data science are fueling Osaka's growth. The city is emerging as a hub of digital transformation, building the foundation for next-generation industries.
2021 to 2024 saw between eight and fourteen Kansai startups achieve IPO annually, pushing the region to the forefront of Japan's startup ecosystem.
Osaka alone is home to over 380 university-originated startups, ranking second only to Tokyo nationwide. When joined with other areas in Kansai, like Kyoto and Hyogo, Kansai proves fertile soil for university spinouts.
Between 2020 and 2023, startups in Osaka, Kyoto, and Hyogo collectively raised over 490 billion yen. Osaka in particular more than doubled funds raised, from ¥111B in 2020 to ¥237B in 2023.
Osaka's university-originated startups offer an excellent spread, from life sciences (24%) and software (23%) to energy (15%) and robotics (12%).